Indolo[2,3-b]quinoline Derivatives as Novel Promising Antitumor Agents
نویسندگان
چکیده
Chemistry Dept., Pharmaceutical Research Institute, Rydygiera St. 8, 01-793 Warszawa; Faculty of Biotechnology, Wrocław University, Fryderyk Joliot-Curie St. 14a, 50-383 Wrocław; Faculty of Chemistry, Wroclaw University of Technology, C.K. Norwid St.4/6, 50373 Wrocław; Experimental Acticancer Therapy Laboratory, Institute of Immunology and Experimental Therapy of Polish Academy of Sciences, Rudolfa Weigla St., 53-114 Wrocław
منابع مشابه
The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: highly selective cytotoxic agents.
The synthesis of indolo[2,3-b]quinoline derivatives containing guanidine, amino acid or guanylamino acid substituents as well as their in vitro evaluation for the cytotoxic and antifungal activity are reported. The influence of the guanidine group on the selective cytotoxic and hemolytic properties of indolo[2,3-b]quinoline was investigated. Most of the compounds displayed a high cytotoxic acti...
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